Network Partner

Jan-Åke Gustafsson M.D. Ph.D. Professor Dept of Biosciences and Nutrition Karolinska Institutet SE-141 86 Stockholm, Sweden Phone: +46-(0)8-585 837 46 Fax: +46-(0)8-779 87 95 e-mail: jan-ake.gustafsson@ki.se Personal web page

In cell nuclei there are receptors ready to capture hormone molecules. World-leading research on such nuclear receptors is being run by Professor Jan-Åke Gustafsson's research group at the Department of Biosciences and Nutrition. The work of the group is laying important foundations, especially for the development of new drugs.

• News:
• Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses
• GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response